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Anti-IL23A MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7482)

This product is comprised of an Human Anti-IL23A IgG2-lambda (Clone 3) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • IL23A
  • Alternative Names
  • IL23A; IL-23; IL-23A; IL23P19; P19; SGRF; Interleukin 23; interleukin 23 subunit alpha
  • Overview
  • IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration into tumours. IL-23 mediates its effects on both innate and adaptive arms of the immune system that express the IL-23 receptor. Th17 cells represent the most prominent T cell subset that responds to IL-23, although IL-23 has been implicated in inhibiting the development of regulatory T cell development in the intestine. Th17 cells produce IL-17, a proinflammatory cytokine that enhances T cell priming and stimulates the production of other proinflammatory molecules such as IL-1, IL-6, TNF-alpha, NOS-2, and chemokines resulting in inflammation.
  • Overview
  • Human Anti-IL23A IgG2-lambda (Clone 3)
  • Species Reactivity
  • Human
  • Name
  • iFluor® 450 Succinimidyl Ester
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 451/502
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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CAMouse™-Fully Human Antibody Generation Platform
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CAMouse™-Fully Human Antibody Generation Platform
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