This product is comprised of an Humanized Anti-IL2RA IgG1-kappa antibody (Clone 4) labeled with iFluor® 532 Succinimidyl Ester. iFluor® 532 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
- Alternative Names
- IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
- Overview
- The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
ANTIBODY
- Overview
- Humanized Anti-IL2RA IgG1-kappa antibody (Clone 4)
DYE
- Name
- iFluor® 532 Succinimidyl Ester
- Excitation⁄Emission (nm)
- 537/560
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products