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- Anti-IL2RA MAb (Clone 5)-iFluor® 440 Succinimidyl Ester
Anti-IL2RA MAb (Clone 5)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5671)
This product is comprised of an Chimeric Anti-IL2RA IgG1-kappa (Clone 5) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- IL2RA
- Alternative Names
- IL-2-RA; IL-2 receptor subunit alpha; CD25; TCGFR; TAC antigen; IL2R; CD antigen CD25; Interleukin-2 receptor subunit alpha; IL-2R subunit alpha; p55; IL2-RA; IDDM10
- Overview
- The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
- Overview
- Chimeric Anti-IL2RA IgG1-kappa (Clone 5)
- Species Reactivity
- Human
- Name
- iFluor® 440 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 434/480
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| ADC-W-1372 | Anti-IL2RA (Daclizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1371 | Anti-IL2RA (Daclizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1366 | Anti-IL2RA (Basiliximab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1373 | Anti-IL2RA (Daclizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1367 | Anti-IL2RA (Basiliximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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