- Home
- Products
- Customized FluoroAb™
- IL6
- Anti-IL6 MAb (Clone 12)-iFluor® 514 Succinimidyl Ester
Anti-IL6 MAb (Clone 12)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12118)
This product is comprised of an Chimeric Anti-IL6 IgG1-kappa (Clone 12) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- IL6
- Alternative Names
- IL6; BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2; interleukin 6
- Overview
- Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory muscle factor. In humans, it is encoded by the IL6 gene.
In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Many vascular smooth muscle cells also produce IL-6 as a proinflammatory cytokine. The role of IL-6 as an anti-inflammatory actin is mediated by its inhibitory effect on TNF-α and IL-1 and the activation of IL-1ra and IL-10.
Early evidence suggests that in the context of a broader coronavirus pandemic, IL-6 can be used as an inflammatory marker of severe COVID-19 infection with a poor prognosis.
- Overview
- Chimeric Anti-IL6 IgG1-kappa (Clone 12)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CD4 MAb (Clone 38)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5785)
- Anti-TNFRSF8 MAb (Clone 11)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9601)
- Anti-CD5 MAb (Clone 3)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10420)
- Mogamulizumab-iFluor 405 (CAT#: ADC-FL-326)
- Anti-IL4 MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14474)
- Anti-MYL MAb (Clone 8)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16989)
- Anti-CXCR4 MAb (Clone 1)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS422)
- Anti-FOLR1 MAb (Clone 7)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14842)
- Anti-CD4 MAb (Clone 11)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11910)
- Anti-LY6E MAb (Clone 1)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS15770)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS12118. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1439 | Anti-IL6 (Elsilimomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1440 | Anti-IL6 (Elsilimomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1436 | Anti-IL6 (Elsilimomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2247 | Anti-IL6 (Enlimomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1438 | Anti-IL6 (Elsilimomab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
