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Anti-IL6 MAb (Clone 12)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12118)


  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • IL6
  • Alternative Names
  • IL6; BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2; interleukin 6
  • Overview
  • Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory muscle factor. In humans, it is encoded by the IL6 gene.

    In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Many vascular smooth muscle cells also produce IL-6 as a proinflammatory cytokine. The role of IL-6 as an anti-inflammatory actin is mediated by its inhibitory effect on TNF-α and IL-1 and the activation of IL-1ra and IL-10.

    Early evidence suggests that in the context of a broader coronavirus pandemic, IL-6 can be used as an inflammatory marker of severe COVID-19 infection with a poor prognosis.
  • Overview
  • Chimeric Anti-IL6 IgG1-kappa (Clone 12)
  • Species Reactivity
  • Human
  • Name
  • iFluor® 514 Succinimidyl Ester
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 511/527
  • Detection method
  • Fluorescent

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ADC-W-2246 Anti-IL6 (Enlimomab)-SMCC-DM1 ADC SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
ADC-W-2248 Anti-IL6 (Enlimomab)-MC-MMAF ADC MC (maleimidocaproyl) MMAF
ADC-W-2247 Anti-IL6 (Enlimomab)-SPDB-DM4 ADC SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
ADC-W-1434 Anti-IL6-MC-Vc-PAB-SN38 ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin)
ADC-W-2251 Anti-IL6 (Enlimomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC MC-Vc-PAB-DMEA-(PEG2) duocarmycin SA

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