Anti-IL9 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester
Anti-IL9 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (WJY0-LS7516)
This product is comprised of an Humanized Anti-IL9 IgG1-kappa (Clone 1) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.