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- Anti-ITGA4 MAb (Clone 5)-iFluor® 532 Succinimidyl Ester
Anti-ITGA4 MAb (Clone 5)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12950)
This product is comprised of an Humanized Anti-ITGA4 IgG1-kappa antibody (Clone 5) labeled with iFluor® 532 Succinimidyl Ester. iFluor® 532 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- ITGA4
- Alternative Names
- ITGA4; CD49D; IA4; integrin subunit alpha 4
- Overview
- CD49d is the integrin alpha subunit. It constitutes half of the homing receptors of α4β1 lymphocytes.The product of this gene belongs to the integrin alpha chain protein family. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. This gene encodes the α4 chain. Unlike other integrin α chains, α4 contains neither an I domain nor undergoes disulfide bond cleavage. The Alpha 4 chain is associated with the beta 1 chain or beta 7 chain.
- Overview
- Humanized Anti-ITGA4 IgG1-kappa antibody (Clone 5)
- Species Reactivity
- Human
- Name
- iFluor® 532 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 537/560
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1474 | Anti-ITGA4 (Etrolizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1466 | Anti-ITGA4 (Natalizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1471 | Anti-ITGA4 (Natalizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1476 | Anti-ITGA4 (Etrolizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1469 | Anti-ITGA4 (Natalizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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