Anti-ITGA5 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester
Anti-ITGA5 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester (WJY0-LS8337)
This product is comprised of an Chimeric Anti-ITGA5 IgG4 antibody (Clone 1) labeled with iFluor® 460 Succinimidyl Ester. iFluor® 460 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.