Anti-MUC5AC MAb (Clone 2)-iFluor® 546 Succinimidyl Ester
Anti-MUC5AC MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (WJY0-LS15274)
This product is comprised of an Chimeric Anti-MUC5AC IgG1-kappa (Clone 2) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
Name
MUC5AC
Alternative Names
MUC5AC Peptide
Overview
Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.