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- Anti-NGF MAb (Clone 4)-iFluor® 546 Succinimidyl Ester
Anti-NGF MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15275)
This product is comprised of an Human Anti-NGF IgG4-kappa (Clone 4) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- NGF
- Alternative Names
- Nerve Growth Factor; Nerve Growth Factor (Beta Polypeptide); Beta-NGF; NGFB; Nerve Growth Factor; Beta Subunit; Beta-Nerve Growth Factor; HSAN5;
- Overview
- This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
- Overview
- Human Anti-NGF IgG4-kappa (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1672 | Anti-NGF (Tanezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1663 | Anti-NGF (Fulranumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1674 | Anti-NGF (Tanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1664 | Anti-NGF -SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1666 | Anti-NGF -MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
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