- Home
- Products
- Customized FluoroAb™
- NOTCH1
- Anti-NOTCH1 MAb (Clone 2)-iFluor® 514 Succinimidyl Ester
Anti-NOTCH1 MAb (Clone 2)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12403)
This product is comprised of an Humanized Anti-NOTCH1 IgG2-lambda (Clone 2) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- NOTCH1
- Alternative Names
- Notch 1; Translocation-Associated Notch Protein TAN-1; TAN1; HN1; Notch (Drosophila) Homolog 1 (Translocation-Associated); Notch Homolog 1; Translocation-Associated (Drosophila); Notch Homolog 1; Translocation-Associated;
- Overview
- This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
- Overview
- Humanized Anti-NOTCH1 IgG2-lambda (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-TNFRSF10B MAb (Clone 5)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9939)
- Anti-CD79B MAb (Clone 14)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11620)
- Anti-CTLA4 MAb (Clone 6)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5852)
- Pertuzumab-iFluor 532 (CAT#: ADC-FL-1372)
- Anti-EGFR MAb (Clone 13)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14333)
- Anti-MUC16 MAb (Clone 11)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9901)
- Anti-EGFR MAb (Clone 8)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS242)
- Anti-CD19 MAb (Clone 4)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9627)
- Anti-EGFR MAb (Clone 22)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7000)
- Anti-CD40 MAb (Clone 17)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4263)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS12403. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2362 | Anti-NOTCH1 (Brontictuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2363 | Anti-NOTCH1 (Brontictuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-2360 | Anti-NOTCH1 (Brontictuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2365 | Anti-NOTCH1 (Brontictuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-2364 | Anti-NOTCH1 (Brontictuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
