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NOTCH3
Anti-NOTCH3 MAb (Clone 1)-iFluor® 350 Succinimidyl Ester

Anti-NOTCH3 MAb (Clone 1)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS526)

Name: Anti-NOTCH3 MAb (Clone 1)-iFluor® 350 Succinimidyl Ester
SKU: WJY0-LS526
Rating: 5 (1 reviews)

This product is comprised of an Anti-NOTCH3 Antibody (Clone 1) labeled with iFluor® 350 Succinimidyl Ester. iFluor® 350 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 345/450 nm.

TARGET
ANTIBODY
DYE

Name
NOTCH3

Alternative Names
Notch 3; Neurogenic Locus Notch Homolog Protein 3; Notch (Drosophila) Homolog 3; Notch Homolog 3 (Drosophila); Notch Homolog 3; CADASIL1;

Overview
This gene encodes the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]