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- Anti-NOTCH3 MAb (Clone 2)-iFluor® 488 Succinimidyl Ester
Anti-NOTCH3 MAb (Clone 2)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10291)
This product is comprised of an Human Anti-NOTCH3 IgG2-kappa (Clone 2) labeled with iFluor® 488 Succinimidyl Ester. iFluor® 488 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- NOTCH3
- Alternative Names
- Notch 3; Neurogenic Locus Notch Homolog Protein 3; Notch (Drosophila) Homolog 3; Notch Homolog 3 (Drosophila); Notch Homolog 3; CADASIL1;
- Overview
- This gene encodes the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
- Overview
- Human Anti-NOTCH3 IgG2-kappa (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 488 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 491/516
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-559 | Anti-NOTCH3-MMAE ADC | MMAE (Monomethyl auristatin E) |
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