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- Anti-PDGFRA MAb (Clone 2)-iFluor® 430 Succinimidyl Ester
Anti-PDGFRA MAb (Clone 2)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3760)
- TARGET
- ANTIBODY
- DYE
- Name
- PDGFRA
- Alternative Names
- alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; CD140a; EC 2.7.10; EC 2.7.10.1; MGC74795; PDGF R alpha; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA BCR fusion; PDGF-R-alpha; platelet-derived growth factor receptor; alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
- Overview
- PDGFRA, platelet-derived growth factor receptor A, also known as PDGFRα, platelet-derived growth factor receptor α, or CD140a, differentiation cluster 140a, is a receptor located on the surface of various cell types. The receptor binds to certain isoforms of platelet-derived growth factor (PDGF), thereby becoming active in cell signaling pathways that stimulate reactions that cause reactions such as cell growth and differentiation. This receptor is essential for the development of certain tissues and organs during embryogenesis and for maintaining them throughout life, especially blood tissues. The mutation in the gene encoding PDGFRA, the PDGFRA gene, is associated with a series of clinically significant tumors.
- Overview
- Human Anti-PDGFRA IgG2-kappa antibody (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 430 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 433/498
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1710 | Anti-PDGFR (Olaratumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1711 | Anti-PDGFR (Olaratumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1717 | Anti-PDGFR (Tovetumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1713 | Anti-PDGFR (Tovetumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1709 | Anti-PDGFR (Olaratumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
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