Anti-ROR1 MAb (Clone 1)-iFluor® 440 Succinimidyl Ester (WJY0-LS5056)

This product is comprised of an scFv-Fc of Anti-ROR1 Antibody (Clone 1) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

 TARGET

  • Name
  • ROR1
  • Alternative Names
  • Neurotrophic Tyrosine Kinase; Receptor-Related 1; NTRKR1
  • Overview
  • This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

 ANTIBODY

  • Overview
  • scFv-Fc of Anti-ROR1 Antibody (Clone 1)
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor® 440 Succinimidyl Ester
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 434/480
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


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