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- Anti-ROR1 MAb (Clone 2)-iFluor® 405 Succinimidyl Ester
Anti-ROR1 MAb (Clone 2)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2548)
- TARGET
- ANTIBODY
- DYE
- Name
- ROR1
- Alternative Names
- Neurotrophic Tyrosine Kinase; Receptor-Related 1; NTRKR1
- Overview
- This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
- Overview
- Humanized Anti-ROR1 IgG1-kappa (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
Published Data
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Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-434 | Anti-ROR1 scFv-Fc-Sec ADC | engineered selenocysteine (Sec) residue |
For Research Use Only. NOT FOR CLINICAL USE.
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