Anti-TNFRSF10B MAb (Clone 6)-iFluor® 532 Succinimidyl Ester (WJY0-LS13277)

This product is comprised of an Chimeric Humanized Anti-TNFRSF10B IgG1-kappa (Clone 6) labeled with iFluor® 532 Succinimidyl Ester. iFluor® 532 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
TNFRSF10B

Alternative Names
TRICK2A; TRICK2B; KILLER; TRAILR2; TNF-related apoptosis-inducing ligand receptor 2; DR5; CD antigen CD262; TRICK2; CD262; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; TRAIL receptor 2; TRICKB; ZTNFR9

Overview
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

ANTIBODY

Overview
Chimeric Humanized Anti-TNFRSF10B IgG1-kappa (Clone 6)

Species Reactivity
Human

DYE

Name
iFluor® 532 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
537/560

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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