Anti-TNFRSF17 MAb (Clone 23)-iFluor® 430 Succinimidyl Ester
Anti-TNFRSF17 MAb (Clone 23)-iFluor® 430 Succinimidyl Ester (WJY0-LS4022)
This product is comprised of an Humanized Anti-TNFRSF17 IgG2-kappa (Clone 23) labeled with iFluor® 430 Succinimidyl Ester. iFluor® 430 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
Name
TNFRSF17
Alternative Names
BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A
Overview
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.