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- Anti-TNFRSF9 MAb (Clone 11)-iFluor® 460 Succinimidyl Ester
Anti-TNFRSF9 MAb (Clone 11)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9221)
This product is comprised of an Chimeric Anti-TNFRSF9 scFv-kappa-heavy (Clone 11) labeled with iFluor® 460 Succinimidyl Ester. iFluor® 460 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- TNFRSF9
- Alternative Names
- ILA; CD137; T-cell antigen 4-1BB homolog; CDw137; T-cell antigen ILA; 4-1BB; CD antigen CD137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor
- Overview
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
- Overview
- Chimeric Anti-TNFRSF9 scFv-kappa-heavy (Clone 11)
- Species Reactivity
- Human
- Name
- iFluor® 460 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 468/493
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1894 | Anti-TNFRSF9 (Urelumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1896 | Anti-TNFRSF9 (Urelumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1892 | Anti-TNFRSF9 (Urelumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1893 | Anti-TNFRSF9 (Urelumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1897 | Anti-TNFRSF9 (Urelumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
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