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Anti-TACSTD2 (clone C16)-VC-PABC-Aur0101 ADC (ADC-W-563)

This ADC product is comprised of an anti-TACSTD2 monoclonal antibody (clone C16) conjugated via a VC-PABC linker to Aur0101.
  • Antibody clone #
  • C16

 ADC Target

  • Name
  • TACSTD2
  • Alternative Names
  • TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic ca
  • Target Entrez Gene ID
  • 4070
  • Overview
  • This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

 ADC Antibody

  • Overview
  • Anti-TACSTD2 Antibody, clone # C16
  • Clone #
  • C16
  • Species Reactivity
  • Human

 ADC Linker

  • Name
  • VC-PABC (valine-citrulline-p-aminobenzylcarbamate)
  • Description
  • Peptide linkers, belonging to Enzymatically cleavable linkers, combine greater systemic stability with rapid enzymatic release of the drug in the target cell. The scission of peptidic bonds relies on lysosomal proteolytic enzymes, which have very low activities in blood due to endogenous inhibitors and the unfavorably high pH value of blood.

 ADC payload drug

  • Name
  • Aur0101

For Research Use Only. NOT FOR CLINICAL USE.

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