ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-M0508	Mal-PEG6-NHS ester	1599472-25-9		530.5	95%		Inquiry
ADC-L-M0509	Mal-PEG8-NHS ester	2055033-05-9		618.6	95%		Inquiry
ADC-L-M0510	Mal-PEG12-NHS ester				95%		Inquiry
ADC-L-M0511	Mal-PEG1-PFP	1807530-08-0		379.2	95%		Inquiry
ADC-L-M0513	Mal-PEG3-PFP	1807534-78-6		467.3	95%		Inquiry
ADC-L-M0515	Mal-PEG5-PFP	1807512-46-4		555.5	95%		Inquiry
ADC-L-M0516	Mal-PEG6-PFP	1599486-33-5		599.5	95%		Inquiry
ADC-L-M0518	Mal-PEG2-t-butyl ester	1374666-31-5		313.3	95%		Inquiry
ADC-L-M0519	Mal-PEG3-t-butyl ester	518044-35-4		357.4	95%		Inquiry
ADC-L-M0520	Mal-PEG4-t-butyl ester	518044-36-5		401.5	95%		Inquiry
ADC-L-M0521	Mal-PEG5-t-butyl ester	2250216-91-0		445.5	95%		Inquiry
ADC-L-M0522	Mal-PEG6-t-butyl ester	518044-37-6		489.6	95%		Inquiry
ADC-L-M0523	Mal-PEG8-t-butyl ester	2055048-43-4		577.7	95%		Inquiry
ADC-L-M0524	Mal-PEG12-t-butyl ester	1443214-98-9		753.9	95%		Inquiry
ADC-L-M0525	Mal-Amido-PEG4-t-butyl ester	1415800-35-9		472.5	95%		Inquiry
ADC-L-M0527	Mal-PEG3-alcohol	146551-23-7		229.2	95%		Inquiry
ADC-L-M0528	Mal-PEG4-alcohol	1421933-37-0		273.3	95%		Inquiry
ADC-L-M0529	Mal-PEG8-alcohol	2353409-63-7		449.5	95%		Inquiry
ADC-L-M0530	Mal-PEG12-alcohol	58914-60-6		625.7	95%		Inquiry
ADC-L-M0532	Mal-PEG4-amine TFA salt	2221042-92-6		316.4	95%		Inquiry