Drug-linker Complexes

Creative Biolabs offers a large collection of pre-assembled drug-linker complexes for ready-to-go antibody conjugation to speed up new antibody-drug conjugate (ADC) development processes. From well-established compounds such as MC-vc-PAB-MMAE, SMCC/sulfo-SMCC-maytansinoid derivatives to more innovative complex sets including peptide linker-based duocarmycin derivative, pH labile linker-based calicheamicin set… these pre-assembled drug-linker complexes are of high quality (>95% purity) and chemically well-defined using LC-MS and 1HNMR spectroscopy. They are available at quantities ranging from milligram for research and development to gram for large scale preparation or even GMP ADC manufacturing. With toxin targeting defined intracellular targets and linker with various releasing mechanisms, the drug-linker complexes will help promote the progress of customized ADC projects.