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- Clenoliximab-Fluoresein
Clenoliximab-Fluoresein (CAT#: ADC-FL-700)
This product is comprised of an anti-CD4 monoclonal antibody (Clenoliximab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD4
- Alternative Names
- CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Overview
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Overview
- Chimeric Anti-CD4 IgG4-lambda antibody, Clenoliximab
- Generic name
- Clenoliximab
- Species Reactivity
- Human
- Name
- Fluoresein
- Excitation⁄Emission (nm)
- 490/525
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-888 | Anti-CD4 (Cedelizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-891 | Anti-CD4 (Ibalizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-887 | Anti-CD4 (Cedelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-893 | Anti-CD4 (Ibalizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-886 | Anti-CD4 (Cedelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
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