Crenezumab-iFluor 647 (ADC-FL-117)

This product is comprised of an anti-APP monoclonal antibody (Crenezumab) labeled with iFluor 647. iFluor 647 is a far-red-fluorescent dye and it's excitation/emission is 650/665 nm.

 TARGET

  • Name
  • APP
  • Alternative Names
  • APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
  • Overview
  • This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

 ANTIBODY

  • Overview
  • Humanized Anti-APP IgG4-kappa antibody, Gantenerumab
  • Generic name
  • Crenezumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor 647
  • Color
  • Far-red
  • Excitation⁄Emission (nm)
  • 650/665
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


Related Products


Online Inquiry
Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
Project Description:









Customized FluoroAb™

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Contact us
USA
 
 Tel:
 Fax:
 Email:
Europe
 
 Tel:
 Email:
Germany
 
 Tel:
 Email:


Inquiry

Top