Daratumumab-iFluor 405 (ADC-FL-524)

This product is comprised of an anti-CD38 monoclonal antibody (Daratumumab) labeled with iFluor 405. iFluor 405 is a blue-fluorescent dye and it's excitation/emission is 401/421 nm.

 TARGET

  • Name
  • CD38
  • Alternative Names
  • CD38; CD38 molecule; CD38 antigen (p45); ADP-ribosyl cyclase 1; ADP ribosyl cyclase 1; NAD(+) nucleosidase; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; T10;
  • Overview
  • The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

 ANTIBODY

  • Overview
  • Human Anti-CD38 IgG1-kappa antibody, Daratumumab
  • Generic name
  • Daratumumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor 405
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 401/421
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


Related Products


Online Inquiry
Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
Project Description:









Customized FluoroAb™

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Contact us
USA
 
 Tel:
 Fax:
 Email:
Europe
 
 Tel:
 Email:
Germany
 
 Tel:
 Email:


Inquiry

Top