Fmoc-aminooxy-PEG12-acid (ADC-L-Y0263)

Fmoc-aminooxy-PEG12-acid is a PEG derivative with aminooxy group protected by Fmoc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

CAS NO
2055104-72-6

Description
Fmoc-aminooxy-PEG12-acid is a PEG derivative with aminooxy group protected by Fmoc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

Molecular Weight
856

Purity
95%

Formula
C42H65NO17

Group 1
COOR/Ester

Functional Group 1
COOR/Ester

PEG/Non-PEG
PEG

Cleavable/Non-cleavable
Non-cleavable

Group 2
COOH/Carboxylic Acid

Functional Group 2
COOH/Carboxylic Acid

Storage Condition
-20 ° C

Shipping
Ambient Temperature

For Research Use Only. NOT FOR CLINICAL USE.

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