Galiximab-iFluor 488 (ADC-FL-903)

This product is comprised of an anti-CD80 monoclonal antibody (Galiximab) labeled with iFluor 488. iFluor 488 is a green-fluorescent dye and it's excitation/emission is 490/525 nm.

 TARGET

  • Name
  • CD80
  • Alternative Names
  • CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counnternalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
  • Overview
  • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

 ANTIBODY

  • Overview
  • Chimeric Anti-CD80 IgG1-lambda antibody, Galiximab
  • Generic name
  • Galiximab
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor 488
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 490/525
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


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