This product is comprised of an anti-CD80 monoclonal antibody (Galiximab) labeled with iFluor 568. iFluor 568 is a orange-fluorescent dye and it's excitation/emission is 578/603 nm.
TARGET
- Alternative Names
- CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counnternalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
- Overview
- The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
ANTIBODY
- Overview
- Chimeric Anti-CD80 IgG1-lambda antibody, Galiximab
DYE
- Excitation⁄Emission (nm)
- 578/603
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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