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- Galiximab-Fluoresein
Galiximab-Fluoresein (CAT#: ADC-FL-916)
This product is comprised of an anti-CD80 monoclonal antibody (Galiximab) labeled with Fluoresein. Fluoresein is a fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD80
- Alternative Names
- CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counnternalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
- Overview
- The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
- Overview
- Chimeric Anti-CD80 IgG1-lambda antibody, Galiximab
- Generic name
- Galiximab
- Species Reactivity
- Human
- Name
- Fluoresein
- Excitation⁄Emission (nm)
- 490/525
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-960 | Anti-CD80 (Galiximab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-957 | Anti-CD80 (Galiximab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-959 | Anti-CD80 (Galiximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-958 | Anti-CD80 (Galiximab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-956 | Anti-CD80 (Galiximab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
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