Linker-Toxin SET, this set is made by Monomethyl auristatin E (MMAE) conjugated to the lysosomally cleavable Gly3-vc-PAB linker. MMAE, a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Description
Linker-Toxin SET, this set is made by Monomethyl auristatin E (MMAE) conjugated to the lysosomally cleavable Gly3-vc-PAB linker. MMAE, a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.