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Anti-TACSTD2 (clone 7E6)-AcLys-VC-PABC-0101 (ADC-W-293)

This ADC product is comprised of an anti-TACSTD2 monoclonal antibody (clone 7E6) conjugated via a AcLys-VC-PABC linker to a drug.
  • Antibody clone #
  • 7E6

 ADC Target

  • Name
  • TACSTD2
  • Alternative Names
  • TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic ca
  • Target Entrez Gene ID
  • 4070
  • Overview
  • This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

 ADC Antibody

  • Overview
  • Humanized Anti-TACSTD2 antibody, clone # 7E6
  • Clone #
  • 7E6
  • Species Reactivity
  • Human

 ADC Linker

  • Name
  • AcLys-VC-
    PABC (Acetyl-lysine-valine-citrulline-p-aminobenzyloxycarbonyl)

 ADC payload drug

  • Name
  • 2-methylalanyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide)

For Research Use Only. NOT FOR CLINICAL USE.

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