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- Ibalizumab-Cy5
Ibalizumab-Cy5 (CAT#: ADC-FL-717)
- TARGET
- ANTIBODY
- DYE
- Name
- CD4
- Alternative Names
- CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Overview
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Overview
- Humanized Anti-CD4 IgG4-kappa antibody, Ibalizumab
- Generic name
- Ibalizumab
- Species Reactivity
- Human
- Name
- Cy5
- Color
- Far-red
- Excitation⁄Emission (nm)
- 649/666
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-890 | Anti-CD4 (Ibalizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-883 | Anti-CD4 (Clenoliximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-891 | Anti-CD4 (Ibalizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-886 | Anti-CD4 (Cedelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-892 | Anti-CD4 (Ibalizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
For Research Use Only. NOT FOR CLINICAL USE.
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