- Home
- Products
- Customized FluoroAb™
- FLT1
- Icrucumab-iFluor 680
Icrucumab-iFluor 680 (CAT#: ADC-FL-1486)
This product is comprised of an anti-FLT1 monoclonal antibody (Icrucumab) labeled with iFluor 680. iFluor 680 is a near-IR-fluorescent dye and it's excitation/emission is 679/702 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- FLT1
- Alternative Names
- FLT1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FLT; vascular endothelial growth factor receptor 1; VEGFR1; FLT-1; VEGFR-1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT;
- Overview
- This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
- Overview
- Human Anti-FLT1 IgG1-kappa antibody, Icrucumab
- Generic name
- Icrucumab
- Species Reactivity
- Human
- Name
- iFluor 680
- Color
- Near-IR
- Excitation⁄Emission (nm)
- 679/702
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-1486. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1151 | Anti-FLT1 (Icrucumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1152 | Anti-FLT1 (Icrucumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1148 | Anti-FLT1 (Icrucumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1153 | Anti-FLT1 (Icrucumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1149 | Anti-FLT1 (Icrucumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-MUC1 MAb (Clone 12)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11574)
- Anti-MET MAb (Clone 10)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7555)
- Anti-PDCD1 MAb (Clone 27)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15315)
- Anti-IFNA1 MAb (Clone 2)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9834)
- Bertilimumab-iFluor 350 (CAT#: ADC-FL-289)
- Anti-IGF1 MAb (Clone 8)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16667)
- Anti-IL5 MAb (Clone 5)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13649)
- Anti-CSF2 MAb (Clone 3)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10456)
- Anti-C5 MAb (Clone 22)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS7821)
- Anti-GD2 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15418)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
