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Ipilimumab-Coumarin (CAT#: ADC-FL-1039)


  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • CTLA4
  • Alternative Names
  • CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3 , CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; GRD4; CTLA-4; IDDM12; CELIAC3;
  • Overview
  • This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
  • Overview
  • Human Anti-CTLA4 IgG1-kappa antibody, Ipilimumab
  • Generic name
  • Ipilimumab
  • Species Reactivity
  • Human
  • Name
  • Coumarin
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 387/470
  • Detection method
  • Fluorescent

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Other Products

Same Target
CAT# Product Name Linker Payload
ADC-W-1000 Anti-CTLA4 (Ipilimumab)-MC-MMAF ADC MC (maleimidocaproyl) MMAF
ADC-W-1007 Anti-CTLA4 (Ticilimumab)-MC-Vc-PAB-MMAE ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE
ADC-W-1002 Anti-CTLA4 (Ipilimumab)-MC-Vc-PAB-SN38 ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin)
ADC-W-1001 Anti-CTLA4 (Ipilimumab)-MC-Vc-PAB-MMAE ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE
ADC-W-1008 Anti-CTLA4 (Ticilimumab)-MC-Vc-PAB-SN38 ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin)

For Research Use Only. NOT FOR CLINICAL USE.

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