This product is comprised of an anti-CD6 monoclonal antibody (Itolizumab) labeled with iFluor 488. iFluor 488 is a green-fluorescent dye and it's excitation/emission is 490/525 nm.
TARGET
- Alternative Names
- CD6; CD6 molecule; CD6 antigen; T-cell differentiation antigen CD6; Tp120; T12; TP120; FLJ44171;
- Overview
- This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
ANTIBODY
- Overview
- Humanized Anti-CD6 IgG1-kappa antibody, Itolizumab
DYE
- Excitation⁄Emission (nm)
- 490/525
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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