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- Itolizumab-Coumarin
Itolizumab-Coumarin (CAT#: ADC-FL-877)
This product is comprised of an anti-CD6 monoclonal antibody (Itolizumab) labeled with Coumarin. Coumarin is a blue-fluorescent dye and it's excitation/emission is 387/470 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD6
- Alternative Names
- CD6; CD6 molecule; CD6 antigen; T-cell differentiation antigen CD6; Tp120; T12; TP120; FLJ44171;
- Overview
- This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
- Overview
- Humanized Anti-CD6 IgG1-kappa antibody, Itolizumab
- Generic name
- Itolizumab
- Species Reactivity
- Human
- Name
- Coumarin
- Color
- Blue
- Excitation⁄Emission (nm)
- 387/470
- Detection method
- Fluorescent
Published Data
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Scientific Resources
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-946 | Anti-CD6 (Itolizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-947 | Anti-CD6 (Itolizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-944 | Anti-CD6 (Itolizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-948 | Anti-CD6 (Itolizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-949 | Anti-CD6 (Itolizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
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