Keliximab-Alexa 647 (ADC-FL-657)

This product is comprised of an anti-CD4 monoclonal antibody (Keliximab) labeled with Alexa Fluor 647. Alexa Fluor 647 is a far-red-fluorescent dye and it's excitation/emission is 650/665 nm.

 TARGET

  • Name
  • CD4
  • Alternative Names
  • CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
  • Overview
  • This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

 ANTIBODY

  • Overview
  • Chimeric Anti-CD4 IgG12-lambda antibody, Keliximab
  • Generic name
  • Keliximab
  • Host animal
  • primate
  • Species Reactivity
  • Human

 DYE

  • Name
  • Alexa Fluor 647
  • Color
  • Far-red
  • Excitation⁄Emission (nm)
  • 650/665
  • Detection method
  • Fluorescent

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