Anti-TNFRSF8 (clone Ki4) scFv-MAP ADC (ADC-W-354)

This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (clone Ki4) conjugated via a linker to a MAP.
  • Antibody clone #
  • Ki4(scFv)

 ADC Target

  • Name
  • Alternative Names
  • TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30;
  • Target Entrez Gene ID
  • 943
  • Overview
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

 ADC Antibody

  • Overview
  • Anti-TNFRSF8 Antibody scFv, clone # Ki4(scFv)
  • Clone #
  • Ki4(scFv)
  • Species Reactivity
  • Human

 ADC payload drug

  • Name
  • human pro-apoptotic effector protein, microtubule-associated protein tau (MAPT)

For lab research use only, not for any in vivo human use.

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