- Home
- Products
- Customized ADCs
- TNFRSF8
- Anti-TNFRSF8 scFv-MAP ADC-15
Anti-TNFRSF8 scFv-MAP ADC-15 (CAT#: ADC-W-354)
This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (clone Ki4) conjugated via a linker to a MAP.
- Product Information
- ADC Target
- ADC Antibody
- ADC payload drug
- Antibody clone #
- Ki4(scFv)
- Name
- TNFRSF8
- Alternative Names
- TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30;
- Target Entrez Gene ID
- 943
- Target UniProt ID
- A5D8T4
- Overview
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Overview
- Anti-TNFRSF8 Antibody scFv, clone # Ki4(scFv)
- Clone #
- Ki4(scFv)
- Species Reactivity
- Human
- Name
- human pro-apoptotic effector protein, microtubule-associated protein tau (MAPT)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-W-354. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-356 | Anti-CD30 receptorc-Mc-VC-PABC-MMAF ADC-12 | MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAF (Monomethyl auristatin F) |
| ADC-W-1889 | Anti-TNFRSF8 (Iratumumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1887 | Anti-TNFRSF8 (Iratumumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-2345 | Anti-TNFRSF8 (Brentuximab )-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2344 | Anti-TNFRSF8 (Brentuximab )-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-ITGAL (Odulimomab)-SPDB-DM4 ADC (CAT#: ADC-W-1485)
- Anti-ITGA2 (Vatelizumab)-MC-MMAF ADC (CAT#: ADC-W-1456)
- Anti-PCSK9 (Lodelcizumab)-MC-MMAF ADC (CAT#: ADC-W-1690)
- Anti-Rabies Virus Glycoprotein (Foravirumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC (CAT#: ADC-W-1969)
- Anti-CD70-MCC-DM1 ADC (CAT#: ADC-W-487)
- Anti-ERBB3 (Seribantumab)-SPDB-DM4 ADC (CAT#: ADC-W-1125)
- Anti-FOLH1-SMCC-DM1 ADC-3 (CAT#: ADC-W-603)
- Anti-CD33 ADC-1 (CAT#: ADC-W-068)
- Anti-PDGFR (Tovetumab)-SPDB-DM4 ADC (CAT#: ADC-W-1713)
- Anti-CD40 (Lucatumumab)-MC-Vc-PAB-SN38 ADC (CAT#: ADC-W-912)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
