- Home
- Products
- Customized ADCs
- TNFRSF8
- Anti-TNFRSF8 scFv-MAP ADC-15
Anti-TNFRSF8 scFv-MAP ADC-15 (CAT#: ADC-W-354)
This ADC product is comprised of an anti-TNFRSF8 monoclonal antibody (clone Ki4) conjugated via a linker to a MAP.
- Product Information
- ADC Target
- ADC Antibody
- ADC payload drug
- Antibody clone #
- Ki4(scFv)
- Name
- TNFRSF8
- Alternative Names
- TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30;
- Target Entrez Gene ID
- 943
- Target UniProt ID
- A5D8T4
- Overview
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Overview
- Anti-TNFRSF8 Antibody scFv, clone # Ki4(scFv)
- Clone #
- Ki4(scFv)
- Species Reactivity
- Human
- Name
- human pro-apoptotic effector protein, microtubule-associated protein tau (MAPT)
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-TNFRSF8-Mc-PABC-MMAE ADC-12 (CAT#: ADC-W-342)
- Anti-VEGFA (Vanucizumab)-MC-Vc-PAB-SN38 ADC (CAT#: ADC-W-2292)
- Anti-TNFRSF10B (Tigatuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC (CAT#: ADC-W-1885)
- Anti-ITGA4+ITGB7 (Crenezumab)-SMCC-DM1 ADC (CAT#: ADC-W-2498)
- Anti-TNFRSF17-VC-MMAE ADC-10 (CAT#: ADC-W-271)
- Anti-ANGPTL3-MC-Vc-PAB-MMAE ADC (CAT#: ADC-W-2327)
- Anti-IL2RA (Basiliximab)-MC-Vc-PAB-MMAE ADC (CAT#: ADC-W-1367)
- Anti-CMV (Sevirumab)-SMCC-DM1 ADC (CAT#: ADC-W-1976)
- Anti-CD79b-SMCC-DM1 ADC-5 (CAT#: ADC-W-168)
- Anti-CMV (Sevirumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC (CAT#: ADC-W-1981)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-W-354. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-355 | Anti-TNFRSF8 -Mc-MMAF ADC-12 | MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAF (Monomethyl auristatin F) |
| ADC-W-2345 | Anti-TNFRSF8 (Brentuximab )-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1886 | Anti-TNFRSF8 (Iratumumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1888 | Anti-TNFRSF8 (Iratumumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2346 | Anti-TNFRSF8 (Brentuximab )-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
