- Home
- Products
- Customized FluoroAb™
- APP
- Ponezumab-iFluor 350
Ponezumab-iFluor 350 (CAT#: ADC-FL-181)
This product is comprised of an anti-APP monoclonal antibody (Ponezumab) labeled with iFluor 350. iFluor 350 is a blue-fluorescent dye and it's excitation/emission is 346/442 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa antibody, Ponezumab
- Generic name
- Ponezumab
- Species Reactivity
- Human
- Name
- iFluor 350
- Color
- Blue
- Excitation⁄Emission (nm)
- 346/442
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-FUT3 MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6613)
- Anti-TNFRSF17 MAb (Clone 9)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12682)
- Anti-CD22 MAb (Clone 4)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS328)
- Anti-ITGA4+ITGB7 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13095)
- Nimotuzumab-Bodipy FL (CAT#: ADC-FL-1218)
- Anti-CD4 MAb (Clone 31)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11930)
- Anti-FGFR2 MAb (Clone 2)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3328)
- Anti-PROM1 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6549)
- Anti-CD19 MAb (Clone 19)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4001)
- Anti-CD22 MAb (Clone 4)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1866)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-181. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-711 | Anti-APP (Ponezumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-706 | Anti-APP (Bapineuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
