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Propargyl-PEG1-t-butyl ester (ADC-L-195)

Propargyl-PEG1-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
  • CAS NO
  • 488150-84-1
  • Description
  • Propargyl-PEG1-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
  • Molecular Weight
  • 184.2
  • Purity
  • 95%
  • Formula
  • C10H16O3
  • Group 1
  • Alkyne
  • Click Chemistry Group 1
  • Alkyne
  • PEG/Non-PEG
  • PEG
  • Cleavable/Non-cleavable
  • Non-cleavable
  • Group 2
  • COOH/Carboxylic Acid
  • Functional Group 2
  • COOH/Carboxylic Acid
  • Storage Condition
  • -20 ° C
  • Shipping
  • Ambient Temperature

For Research Use Only. NOT FOR CLINICAL USE.

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