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- Radretumab-iFluor 750
Radretumab-iFluor 750 (CAT#: ADC-FL-1505)
This product is comprised of an anti-FN1 sdAb (Radretumab) labeled with iFluor 750. iFluor 750 is a near-IR-fluorescent dye and it's excitation/emission is 749/775 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- FN1
- Alternative Names
- FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;
- Overview
- This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.
- Overview
- Human Anti-FN1 sdAb, Radretumab
- Generic name
- Radretumab
- Species Reactivity
- Human
- Name
- iFluor 750
- Color
- Near-IR
- Excitation⁄Emission (nm)
- 749/775
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1159 | Anti-FN1 (Radretumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1155 | Anti-FN1 (Radretumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-507 | Anti-FN1-DM1-SH ADC | disulfide linkers | DM1-SH(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine-SH) |
| ADC-W-508 | Anti-FN1-SIP-DM1-SH ADC | disulfide linkers | DM1-SH(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine-SH) |
| ADC-W-1156 | Anti-FN1 (Radretumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
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