Samalizumab-Coumarin (ADC-FL-427)

This product is comprised of an anti-CD200 monoclonal antibody (Samalizumab) labeled with Coumarin. Coumarin is a blue-fluorescent dye and it's excitation/emission is 387/470 nm.

 TARGET

  • Name
  • CD200
  • Alternative Names
  • CD200; CD200 molecule; antigen identified by monoclonal MRC OX 2 , CD200 antigen , MOX1, MOX2; OX-2 membrane glycoprotein; MRC; OX 2; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; MOX1; MOX2; OX-2;
  • Overview
  • This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

 ANTIBODY

  • Overview
  • Humanized Anti-CD200 IgG2/G4-kappa antibody, Samalizumab
  • Generic name
  • Samalizumab
  • Host animal
  • Mouse
  • Species Reactivity
  • Human

 DYE

  • Name
  • Coumarin
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 387/470
  • Detection method
  • Fluorescent

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