- Home
- Products
- Customized FluoroAb™
- APP
- Solanezumab-iFluor 488
Solanezumab-iFluor 488 (CAT#: ADC-FL-147)
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1, Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG1-kappa antibody, Solanezumab
- Generic name
- Solanezumab
- Species Reactivity
- Human
- Name
- iFluor 488
- Color
- Green
- Excitation⁄Emission (nm)
- 490/525
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-FL-147. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-708 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-TNFRSF9 MAb (Clone 10)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13834)
- Taplitumomab paptox-iFluor 405 (CAT#: ADC-FL-362)
- Anti-CD40LG MAb (Clone 6)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7341)
- Anti-CD33 MAb (Clone 21)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10258)
- Anti-FGFR2 MAb (Clone 7)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS15637)
- Keliximab-iFluor 555 (CAT#: ADC-FL-654)
- Anti-CD2 MAb (Clone 1)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12467)
- Anti-LTA MAb (Clone 5)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16765)
- Anti-EGFR MAb (Clone 17)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3859)
- Ontuxizumab-iFluor 546 (CAT#: ADC-FL-473)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
