Solitomab-Alexa 488 (ADC-FL-1335)

This product is comprised of an anti-EpCAM Bispecific antibody (BiTE) (Solitomab) labeled with Alexa Fluor 488. Alexa Fluor 488 is a green-fluorescent dye and it's excitation/emission is 490/525 nm.

 TARGET

  • Name
  • EpCAM
  • Alternative Names
  • EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2;
  • Overview
  • This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

 ANTIBODY

  • Overview
  • Humanized Anti-EpCAM Bispecific antibody (BiTE), Solitomab
  • Generic name
  • Solitomab
  • Host animal
  • Mouse
  • Species Reactivity
  • Human

 DYE

  • Name
  • Alexa Fluor 488
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 490/525
  • Detection method
  • Fluorescent

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 45-1 Ramsey Road, Shirley, NY 11967, USA
 Tel: 1-631-381-2994
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