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- Sulesomab-iFluor 488
Sulesomab-iFluor 488 (CAT#: ADC-FL-957)
This product is comprised of an anti-CEACAM6 Fab' fragment (Sulesomab) labeled with iFluor 488. iFluor 488 is a green-fluorescent dye and it's excitation/emission is 490/525 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM6
- Alternative Names
- CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL;
- Overview
- This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
- Overview
- Humanized Anti-CEACAM6 IgG1-Fab’ fragment, Sulesomab
- Generic name
- Sulesomab
- Species Reactivity
- Human
- Name
- iFluor 488
- Color
- Green
- Excitation⁄Emission (nm)
- 490/525
- Detection method
- Fluorescent
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-979 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-977 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-975 | Anti-CEACAM6 (Sulesomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-974 | Anti-CEACAM6 (Sulesomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-978 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
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