- Home
- Products
- Customized ADCs
- CEACAM1
- Anti-CEACAM1 scFv-dextran T-40-MMC ADC
Anti-CEACAM1 scFv-dextran T-40-MMC ADC (CAT#: ADC-W-381)
This ADC product is comprised of an anti-CEACAM1 monoclonal antibody(clone T84.66) conjugated via a extran linker T-40 to a MMC.
- Product Information
- ADC Target
- ADC Antibody
- ADC Linker
- ADC payload drug
- Antibody clone #
- anti-CEA scFv T84.66
- Name
- CEACAM1
- Alternative Names
- BGP; BGP1; BGPI
- Target Entrez Gene ID
- 634
- Target UniProt ID
- Q3KRG8
- Overview
- This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
- Overview
- Anti-CEACAM1 Antibody, clone # anti-CEA scFv T84.66
- Clone #
- anti-CEA scFv T84.66
- Species Reactivity
- Human
- Name
- dextran T-40
- Name
- mitomycin (MMC)
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-C-kit-SMCC-DM1 ADC-5 (CAT#: ADC-W-073)
- Anti-EGFR (Cetuximab)-SPDB-DM4 ADC (CAT#: ADC-W-2590)
- Anti-S. aureus ClfA (Tefibazumab)-SPDB-DM4 ADC (CAT#: ADC-W-2133)
- Anti-CD28 (lumretuzumab)-SPDB-DM4 ADC (CAT#: ADC-W-2277)
- Anti-SDC1 (Indatuximab )-SMCC-DM1 ADC (CAT#: ADC-W-2510)
- Anti-ST8SIA1 (Mitumomab)-SPDB-DM4 ADC (CAT#: ADC-W-1779)
- Anti-PCSK9 MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC (CAT#: ADC-W-1687)
- Anti-ITGA2B (Abciximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC (CAT#: ADC-W-1465)
- Anti-CD22-MCC-DM1 ADC-9 (CAT#: ADC-W-626)
- Anti-CD4 (Keliximab)-SMCC-DM1 ADC (CAT#: ADC-W-866)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for ADC-W-381. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-967 | Anti-CEACAM1 (Arcitumomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-962 | Anti-CEACAM1 (Arcitumomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-965 | Anti-CEACAM1 (Arcitumomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-966 | Anti-CEACAM1 (Arcitumomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-964 | Anti-CEACAM1 (Arcitumomab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
