This product is comprised of an anti-AFP monoclonal antibody (Tacatuzumab) labeled with Oregon green. Oregon green is a green-fluorescent dye and it's excitation/emission is 501/526 nm.
TARGET
- Alternative Names
- AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein;
- Overview
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
ANTIBODY
- Overview
- Humanized Anti-AFP IgG1-kappa antibody, Tacatuzumab
DYE
- Excitation⁄Emission (nm)
- 501/526
For Research Use Only. NOT FOR CLINICAL USE.
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