IgG Fab

Immunoglobulin G (IgG) is the most abundant type of antibody found in blood and extracellular fluid and protects body from various bacterial and viral infections by binding those pathogens. IgG antibody is a 150 kDa tetrameric quaternary structure which contains two identical class γ heavy chains of about 50 kDa and two identical light chains of about 25 kDa. The two heavy chains are linked to each other and to a light chain each by disulfide bonds, resulting in a Y-like shape. The antigen-binding (Fab) fragment is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. The variable domain contains the paratope (the antigen-binding site), comprising a set of complementarity determining regions, at the amino terminal end of the monomer. Each arm of the Y thus binds an epitope on the antigen.

Catalog Product name Similar to Antibody Linker Payload Data sheet Inquiry
ADC-AA-017  anti-HIgG(Fab)-C-MMAE ADC anti-human IgG Fab specific polyclonal IgG antibody Cleavable linkers MMAE (Monomethyl auristatin E) Inquiry
ADC-AA-018  anti-HIgG(Fab)-N-DM1 ADC anti-human IgG Fab specific polyclonal IgG antibody Noncleavable linkers DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) Inquiry
If you can’t find your product on this list? Please directly send email to

Online Inquiry
Name:
*Phone:
*E-mail Address:
*Products or Services Interested:
Company/Institution
*Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.


Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.


Contact us
 45-1 Ramsey Road, Shirley, NY 11967, USA
 Tel: 1-631-381-2994
 Fax: 1-631-207-8356
 Email:

Inquiry

Top