Tregalizumab-iFluor 405 (ADC-FL-668)

This product is comprised of an anti-CD4 monoclonal antibody (Tregalizumab) labeled with iFluor 405. iFluor 405 is a blue-fluorescent dye and it's excitation/emission is 401/421 nm.

 TARGET

  • Name
  • CD4
  • Alternative Names
  • CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
  • Overview
  • This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

 ANTIBODY

  • Overview
  • Humanized Anti-CD4 IgG1-kappa antibody, Tregalizumab
  • Generic name
  • Tregalizumab
  • Species Reactivity
  • Human

 DYE

  • Name
  • iFluor 405
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 401/421
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.


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