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- Tregalizumab-iFluor 555
Tregalizumab-iFluor 555 (CAT#: ADC-FL-672)
This product is comprised of an anti-CD4 monoclonal antibody (Tregalizumab) labeled with iFluor 555. iFluor 555 is a fluorescent dye and it's excitation/emission is 555/580 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD4
- Alternative Names
- CD4; CD4 molecule; CD4 antigen (p55) , T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Overview
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Overview
- Humanized Anti-CD4 IgG1-kappa antibody, Tregalizumab
- Generic name
- Tregalizumab
- Species Reactivity
- Human
- Name
- iFluor 555
- Excitation⁄Emission (nm)
- 555/580
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-888 | Anti-CD4 (Cedelizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-889 | Anti-CD4 (Cedelizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-882 | Anti-CD4 (Clenoliximab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-895 | Anti-CD4 (Ibalizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-887 | Anti-CD4 (Cedelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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