Tripolin A (ADC-P-143)

ADCs Toxins, Triptolin A is described as an specific non-ATP competitve Aurora A kinase inhibitor. Tripolin A doesn`t significantly inhibit Aurora B kinase in mammalian cells. Tripolin A reduces localization of pAurora A on spindle microtubules, affects centrosome integrity, spindle formation and lenght and MT dynamitcs in interphase. Tripolin A is a novel small molecule inhibitor of aurora A kinase.

CAS NO
1148118-92-6

Description
ADCs Toxins, Triptolin A is described as an specific non-ATP competitve Aurora A kinase inhibitor. Tripolin A doesn`t significantly inhibit Aurora B kinase in mammalian cells. Tripolin A reduces localization of pAurora A on spindle microtubules, affects centrosome integrity, spindle formation and lenght and MT dynamitcs in interphase. Tripolin A is a novel small molecule inhibitor of aurora A kinase.

Classification
Others

Molecular Weight
253.25

Purity
95%

For Research Use Only. NOT FOR CLINICAL USE.

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